Odds, Picks and Predictions USA vs. Panama

In Sunday football action, United States (6 wins, 2 losses, 4 draws) hosts Panama (5-4-3) at Exploria Stadium in Orlando for the final round of the CONCACAF World Cup qualifiers. Kickoff is scheduled for 7 p.m. ET (on FS1). Below we preview the USA vs. Panama Odds and Linesand make our best World Cup bets, picks and predictions.

The United States drew Mexico 0-0 on Thursday despite several chances in the final third. F-star Christian Pulisic started the game and had the best chance of the game, failing to convert in front of goal.

The United States finished with 9 shots, 4 on target, while Mexico had 11 shots and 2 on target. The United States now hosts Panama. A victory will seal the USMNT’s bid for the Qatar World Cup.

Panama beat the United States 1-0 in Central America on October 21, 2021. Panama had 8 shots and 4 on target, limiting the United States to just 5 shots and none on target.

Panama sit fifth in the CONCACAF table with 18 points and desperately need a few points while Costa Rica are fourth with 19 points. Panama drew against Honduras 1-1 on Thursday.

USA vs. Panama: Odds, Picks & Predictions

Odds provided by Tipico Sportsbook; go to the USA TODAY Sports Scores and Sports Betting Odds center for a complete list. Lines last updated Saturday at 10:32 p.m. ET.

  • Money line: US -230 (bet $230 to win $100) | Panama +670 (bet $100 to win $670) | Draw +350
  • More less : 2.5 (O: -105 | U: -120)


United States 1, Panama 0

Silver Line (ML)


USA (-230) is the best team, but the money line price is too expensive to bet on USA. Typically, when I pass money line value, I like to look at whether both teams will score or not.

Considering the last game between these two teams had only 4 shots on target, I would bet against an abundance of opportunities. However, the BOTH TEAMS SCORING “NO” is priced at -165.

I prefer to play Direct Under as the best bet.

That said, D. Sergino DestM Gio Reina and Pulisic all missed that October game. The bottom two should see plenty of minutes as the USMNT look to lock in their World Cup spot.

Over/Under (O/U)

BET the LESS THAN 2.5 (-120).

The United States had good attempts against Mexico but did not convert. In 12 World Cup qualifying matches, USA have scored 16 goals and conceded only 7.

Panama have scored 15 goals and allowed 14 in 12 matches. USA are 1-6 O/U in their last 7 international matches in all competitions. Panama are 1-4 O/U out of 2.5 overall in their last 5 games.

Given those records and the quality of USA’s defense in the qualifying rounds, I’ll go for under bets, especially since both teams finish one game on Thursday and have another on Wednesday.

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